L-Leucine methyl ester hydrochloride (CAS 7517-19-3) is
a derivative of the essential amino acid leucine, commonly used in peptide synthesis and biochemical research, particularly for studying cell death mechanisms (apoptosis) in immune cells like T cells and NK cells, often appearing as a white powder.
Key Characteristics
Molecular Weight: 181.66 g/mol
CAS Number: 7517-19-3
Appearance: White powder or crystals
Purity: Typically 98% or higher
Melting Point: Around 149-153°C
Uses & Applications
Peptide Synthesis: A building block in solution-phase peptide synthesis.
Immunology Research: Used to induce apoptosis (cell death) in certain immune cells (e.g., cytotoxic T cells, NK cells).
Cancer Research: Investigated in cancer studies due to its cytotoxic effects.
Handling & Hazards
Irritant: Causes skin and serious eye irritation, may cause respiratory irritation (GHS07).
Precautions: Use in well-ventilated areas, wear protective gloves, clothing, and eye protection; avoid breathing dust.
The MSDS hazards include codes for skin and eye irritation, as well as the potential for respiratory issues if the substance is inhaled.
This versatile compound is often used as a building block in the synthesis of peptides and other complex organic molecules. Its appearance is a white crystalline powder, making it easy to handle and use in a variety of laboratory settings.

